Naghavian, R. et al. Microbial peptides activate tumour-infiltrating lymphocytes in glioblastoma. Nature 617, 807–817 (2023).
Jain, A. et al. Guiding intracortical mind tumour cells to an extracortical cytotoxic hydrogel utilizing aligned polymeric nanofibres. Nat. Mater. 13, 308–316 (2014).
Todo, T. et al. Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a section 2 trial. Nat. Med. 28, 1630–1639 (2022).
Sabu, A. et al. Nanomedicines focusing on glioma stem cells. ACS Appl. Mater. Interfaces 15, 158–181 (2023).
Gimple, R. C., Yang, Ok., Halbert, M. E., Agnihotri, S. & Wealthy, J. N. Mind most cancers stem cells: resilience by adaptive plasticity and hierarchical heterogeneity. Nat. Rev. Most cancers 22, 497–514 (2022).
Chen, C. et al. Intracavity technology of glioma stem cell–particular CAR macrophages primes locoregional immunity for postoperative glioblastoma remedy. Sci. Transl. Med. 14, eabn1128 (2022).
Pittet, M. J., Michielin, O. & Migliorini, D. Scientific relevance of tumour-associated macrophages. Nat. Rev. Clin. Oncol. 19, 402–421 (2022).
Yu, Y. H. et al. Optogenetic-controlled immunotherapeutic designer cells for post-surgical most cancers immunotherapy. Nat. Commun. 13, 6357 (2022).
Bayik, D. & Lathia, J. D. Most cancers stem cell-immune cell crosstalk in tumour development. Nat. Rev. Most cancers 21, 526–536 (2021).
Feng, Q. S., Fang, W. M., Guo, Y. D., Hu, P. & Shi, J. L. Nebulized remedy of early orthotopic lung most cancers by iron-based nanoparticles: macrophage-regulated ferroptosis of most cancers stem cells. J. Am. Chem. Soc. 145, 24153–24165 (2023).
Zhang, Z., He, C. L. & Chen, X. S. Designing hydrogels for immunomodulation in most cancers remedy and regenerative medication. Adv. Mater. 36, 2308894 (2023).
Choudhury, A. R., Gupta, S., Chaturvedi, P. Ok., Kumar, N. & Pandey, D. Mechanobiology of most cancers stem cells and their area of interest. Most cancers Microenviron. 12, 17–27 (2019).
Dong, L. Q. et al. Chiral geometry regulates stem cell destiny and exercise. Biomaterials 222, 119456 (2019).
Ma, B. J. & Bianco, A. Regulation of organic processes by intrinsically chiral engineered supplies. Nat. Rev. Mater. 8, 403–413 (2023).
Furnari, F. B., Cloughesy, T. F., Cavenee, W. Ok. & Mischel, P. S. Heterogeneity of epidermal development issue receptor signalling networks in glioblastoma. Nat. Rev. Most cancers 15, 302–310 (2015).
Sharma, P. et al. Immune checkpoint therapy-current views and future instructions. Cell 186, 1652–1669 (2023).
Wan, S. S. et al. Tumor-associated macrophages produce interleukin 6 and sign through STAT3 to advertise growth of human hepatocellular carcinoma stem cells. Gastroenterology 147, 1393–1404 (2014).
Shi, Y. et al. Tumour-associated macrophages secrete pleiotrophin to advertise PTPRZ1 signalling in glioblastoma stem cells for tumour development. Nat. Commun. 8, 15080 (2017).
Liu, F. Ok. et al. CTLA-4 correlates with immune and medical traits of glioma. Most cancers Cell Int. 20, 7 (2020).
Hirata, N. et al. Remodeling development issue beta promotes the growth of most cancers stem cells through S1PR3 by ligand-independent notch activation. Biol. Pharm. Bull. 45, 649–658 (2022).
Chen, T. L. et al. Twin function of WNT5A in selling endothelial differentiation of glioma stem cells and angiogenesis of glioma derived endothelial cells. Oncogene 40, 5081–5094 (2021).
Barinov, A. et al. Important function of immobilized chemokine CXCL12 within the regulation of the humoral immune response. Proc. Natl Acad. Sci. USA 114, 2319–2324 (2017).
Bleau, A. M. et al. PTEN/PI3K/Akt pathway regulates the aspect inhabitants phenotype and ABCG2 exercise in glioma tumor stem-like cells. Cell Stem Cell 4, 226–235 (2009).
Liu, J. X. et al. Fabrication of a chiral luminescent hydrogel from gold nanoclusters through molecular recognition. Chem. Commun. 57, 10202–10205 (2021).
Koifman, N. & Talmon, Y. Cryogenic electron microscopy methodologies as analytical instruments for the research of self-assembled pharmaceutics. Pharmaceutics 13, 1015 (2021).
Koo, S. et al. Ceria-vesicle nanohybrid therapeutic for modulation of innate and adaptive immunity in a collagen-induced arthritis mannequin. Nat. Nanotechnol. 18, 1502–1514 (2023).
Cui, T. T. et al. A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for most cancers remedy. Nat. Commun. 14, 1974 (2023).
Solar, L. et al. Synthesis of erythrocyte nanodiscs for bacterial toxin neutralization. Angew. Chem. Int. Ed. 62, e202301566 (2023).
Zhang, Q. Z. et al. Neutrophil membrane-coated nanoparticles inhibit synovial irritation and alleviate joint harm in inflammatory arthritis. Nat. Nanotechnol. 13, 1182–1190 (2018).
Kahlert, U. D., Nikkhah, G. & Maciaczyk, J. Epithelial-to-mesenchymal(-like) transition as a related molecular occasion in malignant gliomas. Most cancers Lett. 331, 131–138 (2013).
Liu, Q. P., Luo, Q., Ju, Y. & Music, G. B. Position of the mechanical microenvironment in most cancers improvement and development. Most cancers Biol. Med. 17, 282–292 (2020).
Ohta, Y. et al. Cell-matrix interface regulates dormancy in human colon most cancers stem cells. Nature 608, 784–794 (2022).
Driskill, J. H. & Pan, D. J. Management of stem cell renewal and destiny by YAP and TAZ. Nat. Rev. Mol. Cell Biol. 24, 895–911 (2023).
Bassey-Archibong, B. I. et al. An HLA-G/SPAG9/STAT3 axis promotes mind metastases. Proc. Natl. Acad. Sci. USA 120, e2205247120 (2023).
Guo, Q. et al. NF-κB in biology and focused remedy: new insights and translational implications. Sign Transduct. Goal. Ther. 9, 53 (2024).
Jia, T. T. et al. Atomically exact gold-levonorgestrel nanocluster as a radiosensitizer for enhanced most cancers remedy. ACS Nano 13, 8320–8328 (2019).
Value, J. M., Prabhakaran, A. & West, C. M. L. Predicting tumour radiosensitivity to ship precision radiotherapy. Nat. Rev. Clin. Oncol. 20, 83–98 (2023).
Jezierzański, M. et al. Temozolomide (TMZ) within the remedy of glioblastoma multiforme-a literature overview and medical outcomes. Curr. Oncol. 31, 3994–4002 (2024).
Noffsinger, B. et al. Technical selections considerably alter the adaptive immune response towards immunocompetent murine gliomas in a model-dependent method. J. Neuro-Oncol. 154, 145–157 (2021).
Jacob, F. et al. A patient-derived glioblastoma organoid mannequin and biobank recapitulates inter- and intra-tumoral heterogeneity. Cell 180, 188–204 (2020).
Gao, J. C. et al. Intracerebral destiny of natural and inorganic nanoparticles depends on microglial extracellular vesicle perform. Nat. Nanotechnol. 19, 376–386 (2024).
Aldape, Ok. et al. Challenges to curing main mind tumours. Nat. Rev. Clin. Oncol. 16, 509–520 (2019).
Shen, S. Y. et al. A nanotherapeutic technique to beat chemotherapeutic resistance of most cancers stem-like cells. Nat. Nanotechnol. 16, 104–113 (2021).
Zhang, Z. J., Deng, Q. Y., Xiao, C., Li, Z. F. & Yang, X. L. Rational design of nanotherapeutics primarily based on the 5 options precept for potent elimination of most cancers stem cells. Acc. Chem. Res. 55, 526–536 (2022).
Wang, F. H. et al. Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative remedy of glioblastoma. Proc. Natl Acad. Sci. USA 120, e2204621120 (2023).
Desai, N., Tambe, V., Pofali, P. & Vora, L. Ok. Cell membrane-coated nanoparticles: a brand new frontier in immunomodulation. Adv. NanoBiomed Res. 4, 2400012 (2024).
Cirigliano, S. M. & Fantastic, H. A. Bridging the hole between tumor and illness: innovating most cancers and glioma fashions. J. Exp. Med. 222, e20220808 (2025).
Bonosi, L. et al. Maximal secure resection in glioblastoma surgical procedure: a scientific overview of superior intraoperative image-guided strategies. Mind Sci. 13, 216 (2023).
Chen, L., Zhang, Y. Q., Yang, J. X., Hagan, J. P. & Li, M. Vertebrate animal fashions of glioma: understanding the mechanisms and growing new therapies. Biochim. Biophys. Acta 1836, 158–165 (2013).
Bao, S. D. et al. Glioma stem cells promote radioresistance by preferential activation of the DNA harm response. Nature 444, 756–760 (2006).
Zhang, J. et al. Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection. Nat. Nanotechnol. 16, 538–548 (2021).
