6.9 C
Canberra
Friday, May 29, 2026

Chemical efflux imaging utilizing an annular nanosensor array for in situ bladder most cancers detection


  • van Hoogstraten, L. M. et al. World developments within the epidemiology of bladder most cancers: challenges for public well being and medical apply. Nat. Rev. Clin. Oncol. 20, 287–304 (2023).

    Article 
    PubMed 

    Google Scholar
     

  • Kim, J.-S., Lee, J., Nguyen, T. T. & Choi, S. Y. Optimum timing for the primary cystoscopic follow-up utilizing time-to-treatment initiation evaluation of oncologic outcomes in major non-muscle invasive bladder most cancers. Sci. Rep. 14, 8440 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Mossanen, M. & Gore, J. L. The burden of bladder most cancers care: direct and oblique prices. Curr. Opin. Urol. 24, 487–491 (2014).

    Article 
    PubMed 

    Google Scholar
     

  • Sievert, Ok. D. et al. Financial points of bladder most cancers: what are the advantages and prices? World J. Urol. 27, 295–300 (2009).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Tan, W. S., Rodney, S., Lamb, B., Feneley, M. & Kelly, J. Administration of non-muscle invasive bladder most cancers: a complete evaluation of tips from america, Europe and Asia. Most cancers Deal with. Rev. 47, 22–31 (2016).

    Article 
    PubMed 

    Google Scholar
     

  • Grabe-Heyne, Ok. et al. Intermediate and high-risk non-muscle-invasive bladder most cancers: an summary of epidemiology, burden, and unmet wants. Entrance. Oncol. 13, 1170124 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Holzbeierlein, J. M. et al. Analysis and remedy of non-muscle invasive bladder most cancers: AUA/SUO guideline: 2024 modification. J. Urol. 211, 533–538 (2024).

    Article 
    PubMed 

    Google Scholar
     

  • Shkolyar, E. et al. Optimizing cystoscopy and TURBT: enhanced imaging and synthetic intelligence. Nat. Rev. Urol. 22, 46–54 (2025).

    Article 
    PubMed 

    Google Scholar
     

  • Maas, M., Todenhöfer, T. & Black, P. C. Urine biomarkers in bladder most cancers—present standing and future views. Nat. Rev. Urol. 20, 597–614 (2023).

    Article 
    PubMed 

    Google Scholar
     

  • Ng, Ok., Stenzl, A., Sharma, A. & Vasdev, N. Urinary biomarkers in bladder most cancers: A assessment of the present panorama and future instructions. Urologic Oncology: Seminars and Unique Investigations 39, 41–51 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Thomas, C. E., Sexton, W., Benson, Ok., Sutphen, R. & Koomen, J. Urine assortment and processing for protein biomarker discovery and quantification. Most cancers Epidemiol. Biomark. Prev. 19, 953–959 (2010).

    Article 
    CAS 

    Google Scholar
     

  • Lee, S., Oh, J., Cho, M. & Kim, J. Ok. Fluorescence-based microendoscopic sensing system for minimally invasive in vivo bladder most cancers prognosis. Biosensors 12, 631 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Witjes, J. A. et al. Medical and price effectiveness of hexaminolevulinate-guided blue-light cystoscopy: proof assessment and up to date skilled suggestions. Eur. Urol. 66, 863–871 (2014).

    Article 
    PubMed 

    Google Scholar
     

  • Alchera, E. et al. Early prognosis of bladder most cancers by photoacoustic imaging of tumor-targeted gold nanorods. Photoacoustics 28, 100400 (2022).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sim, Ok. C. & Sung, D. J. Function of magnetic resonance imaging in tumor staging and follow-up for bladder most cancers. Transl. Androl. Urol. 9, 2890 (2020).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Simó, C. et al. Urease-powered nanobots for radionuclide bladder most cancers remedy. Nat. Nanotechnol. 19, 554–564 (2024).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hafeez, S. & Huddart, R. Advances in bladder most cancers imaging. BMC Med. 11, 1–10 (2013).

    Article 

    Google Scholar
     

  • Kwong, G. A. et al. Artificial biomarkers: a twenty-first century path to early most cancers detection. Nat. Rev. Most cancers 21, 655–668 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Joice, G. A., Bivalacqua, T. J. & Kates, M. Optimizing pharmacokinetics of intravesical chemotherapy for bladder most cancers. Nat. Rev. Urol. 16, 599–612 (2019).

    Article 
    PubMed 

    Google Scholar
     

  • Sweeney, S. Ok., Luo, Y., O’Donnell, M. A. & Assouline, J. Nanotechnology and most cancers: bettering real-time monitoring and staging of bladder most cancers with multimodal mesoporous silica nanoparticles. Most cancers Nanotechnol. 7, 1–18 (2016).

    Article 

    Google Scholar
     

  • Wu, D. et al. Delicate electrochemical immunosensor for detection of nuclear matrix protein-22 based mostly on NH2-SAPO-34 supported Pd/Co nanoparticles. Sci. Rep. 6, 24551 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Liang, L.-G. et al. An built-in double-filtration microfluidic system for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder most cancers. Sci. Rep. 7, 1–10 (2017).


    Google Scholar
     

  • Peng, C. et al. A colorimetric immunosensor based mostly on self-linkable dual-nanozyme for ultrasensitive bladder most cancers prognosis and prognosis monitoring. Biosens. Bioelectron. 126, 581–589 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Tomiyama, E. et al. EphA2 on urinary extracellular vesicles as a novel biomarker for bladder most cancers prognosis and its impact on the invasiveness of bladder most cancers. Br. J. Most cancers 127, 1312–1323 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Feng, Y. et al. Iodide-enhanced perovskite nanozyme-based colorimetric platform for detection of urinary nuclear matrix protein 22. ACS Appl. Mater. Interfaces 15, 27742–27749 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Li, Q. et al. Choline phosphate-grafted nanozymes as common extracellular vesicle probes for bladder most cancers detection. ACS Nano 18, 16113–16125 (2024).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Music, F.-X. et al. Latest progress in nanomaterial-based biosensors and theranostic nanomedicine for bladder most cancers. Biosensors 13, 106 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hao, L. et al. Microenvironment-triggered multimodal precision diagnostics. Nat. Mater. 20, 1440–1448 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Landry, M. P. et al. Single-molecule detection of protein efflux from microorganisms utilizing fluorescent single-walled carbon nanotube sensor arrays. Nat. Nanotechnol. 12, 368–377 (2017).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang, Y., Li, M., Gao, X., Chen, Y. & Liu, T. Nanotechnology in most cancers prognosis: progress, challenges and alternatives. J. Hematol. Oncol. 12, 1–13 (2019).

    Article 

    Google Scholar
     

  • Hao, L. et al. CRISPR-Cas-amplified urinary biomarkers for multiplexed and transportable most cancers diagnostics. Nat. Nanotechnol. 18, 798–807 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kim, M. et al. Detection of ovarian most cancers through the spectral fingerprinting of quantum-defect-modified carbon nanotubes in serum by machine studying. Nat. Biomed. Eng. 6, 267–275 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lukacz, E. S. et al. A wholesome bladder: a consensus assertion. Int. J. Clin. Pract. 65, 1026–1036 (2011).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Machado, M., Yim, W. & Strano, M. S. A sensor resolution to the femtomolar downside in bladder most cancers. ACS Sens. 10, 6501–6511 (2025).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Erickson, H. P. Dimension and form of protein molecules on the nanometer degree decided by sedimentation, gel filtration, and electron microscopy. Biol. Proced. On-line 11, 32–51 (2009).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zheng, Z., Wan, Q., Meixiong, G. & Du, Q. Cell cycle–regulated membrane binding of NuMA contributes to environment friendly anaphase chromosome separation. Mol. Biol. Cell 25, 606–619 (2014).

    Article 
    PubMed 

    Google Scholar
     

  • Kotak, S., Busso, C. & Gönczy, P. NuMA interacts with phosphoinositides and hyperlinks the mitotic spindle with the plasma membrane. EMBO J. 33, 1815–1830 (2014).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang, W., Ji, X., Kapur, A., Zhang, C. & Mattoussi, H. A multifunctional polymer combining the imidazole and zwitterion motifs as a biocompatible compact coating for quantum dots. JACS 137, 14158–14172 (2015).

    Article 
    CAS 

    Google Scholar
     

  • Silmore, Ok. S., Gong, X., Strano, M. S. & Swan, J. W. Excessive-resolution nanoparticle sizing with most a posteriori nanoparticle monitoring evaluation. ACS Nano 13, 3940–3952 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Park, M. et al. Measuring the accessible floor space inside the nanoparticle corona utilizing molecular probe adsorption. Nano Lett. 19, 7712–7724 (2019).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sánchez-Velázquez, G. et al. Utilizing molecular probe adsorption to characterize the nanoparticle corona part and molecular recognition. Langmuir 41, 17602–17614 (2025).

    Article 
    PubMed 

    Google Scholar
     

  • Miyake, M. et al. Influencing components on the NMP-22 urine assay: an experimental mannequin. BMC Urol. 12, 1–6 (2012).

    Article 

    Google Scholar
     

  • Jamshidian, H., Kor, Ok. & Djalali, M. Urine focus of nuclear matrix protein 22 for prognosis of transitional cell carcinoma of bladder. Urol J. 5, 243–247 (2008).

    PubMed 

    Google Scholar
     

  • Messing, E. M. et al. Impact of intravesical instillation of gemcitabine vs saline instantly following resection of suspected low-grade non-muscle-invasive bladder most cancers on tumor recurrence: SWOG S0337 randomized medical trial. JAMA 319, 1880–1888 (2018).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Cho, S.-Y. et al. Mobile lensing and close to infrared fluorescent nanosensor arrays to allow chemical efflux cytometry. Nat. Commun. 12, 3079 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wu, D. et al. Phenolic-enabled nanotechnology: versatile particle engineering for biomedicine. Chem. Soc. Rev. 50, 4432–4483 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kitazaki, S., Tanaka, A. & Hayashi, N. Sterilization of slim tube inside floor utilizing discharge plasma, ozone, and UV mild irradiation. Vacuum 110, 217–220 (2014).

    Article 
    CAS 

    Google Scholar
     

  • John, J. et al. The porcine mannequin for urological analysis and coaching: an endoscopic and CT-based examine. Uro 6, 7 (2026).

    Article 

    Google Scholar
     

  • Jin, Z. et al. Modification of poly(maleic anhydride)-based polymers with H2N–R nucleophiles: addition or substitution response? Bioconjugate Chem. 30, 871–880 (2019).

    Article 
    CAS 

    Google Scholar
     

  • Zhang, J. et al. Molecular recognition utilizing corona part complexes fabricated from artificial polymers adsorbed on carbon nanotubes. Nat. Nanotechnol. 8, 959–968 (2013).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Yim, W. et al. Polyphenol-stabilized coacervates for enzyme-triggered drug supply. Nat. Commun. 15, 7295 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kilani, R. et al. Selective cytotoxicity of gemcitabine in bladder most cancers cell traces. Anti-Most cancers Medicine 13, 557–566 (2002).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Related Articles

    LEAVE A REPLY

    Please enter your comment!
    Please enter your name here

    [td_block_social_counter facebook="tagdiv" twitter="tagdivofficial" youtube="tagdiv" style="style8 td-social-boxed td-social-font-icons" tdc_css="eyJhbGwiOnsibWFyZ2luLWJvdHRvbSI6IjM4IiwiZGlzcGxheSI6IiJ9LCJwb3J0cmFpdCI6eyJtYXJnaW4tYm90dG9tIjoiMzAiLCJkaXNwbGF5IjoiIn0sInBvcnRyYWl0X21heF93aWR0aCI6MTAxOCwicG9ydHJhaXRfbWluX3dpZHRoIjo3Njh9" custom_title="Stay Connected" block_template_id="td_block_template_8" f_header_font_family="712" f_header_font_transform="uppercase" f_header_font_weight="500" f_header_font_size="17" border_color="#dd3333"]
    - Advertisement -spot_img

    Latest Articles