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Wednesday, March 4, 2026

The Startup Alternative with Gabriela de Queiroz – O’Reilly


Generative AI in the Real World

Generative AI within the Actual World

Generative AI within the Actual World: The Startup Alternative with Gabriela de Queiroz



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Ben Lorica and Gabriela de Queiroz, director of AI at Microsoft, speak about startups: particularly, AI startups. How do you get seen? How do you generate actual traction? What are startups doing with brokers and with protocols like MCP and A2A? And which safety points ought to startups look ahead to, particularly in the event that they’re utilizing open weights fashions?

Try different episodes of this podcast on the O’Reilly studying platform.

In regards to the Generative AI within the Actual World podcast: In 2023, ChatGPT put AI on everybody’s agenda. In 2025, the problem will probably be turning these agendas into actuality. In Generative AI within the Actual World, Ben Lorica interviews leaders who’re constructing with AI. Be taught from their expertise to assist put AI to work in your enterprise.

Factors of Curiosity

  • 0:00: Introduction to Gabriela de Queiroz, director of AI at Microsoft.
  • 0:30: You’re employed with lots of startups and founders. How have the alternatives for startups in generative AI modified? Are the alternatives increasing?
  • 0:56: Completely. The entry barrier for founders and builders is far decrease. Startups are exploding—not simply the quantity but in addition the fascinating issues they’re doing.
  • 1:19: You catch startups after they’re nonetheless exploring, attempting to construct their MVP. So startups should be extra persistent in looking for differentiation. If anybody can construct an MVP, how do you distinguish your self?
  • 1:46: At Microsoft, I drive a number of strategic initiatives to assist growth-stage startups. I additionally information them in fixing actual ache factors utilizing our stacks. I’ve designed applications to highlight founders. 
  • 3:08: I do lots of engagement the place I assist startups go from the prototype or MVP to impression. An MVP shouldn’t be sufficient. I must see an actual use case and I must see some traction. Once they have actual prospects, we see whether or not their MVP is working.
  • 3:49: Are you beginning to see patterns for gaining traction? Are they specializing in a particular area? Or have they got a superb dataset?
  • 4:02: If they’re fixing an actual use case in a particular area or area of interest, that is the place we see them succeed. They’re fixing an actual ache, not constructing one thing generic. 
  • 4:27: We’re each in San Francisco, and fixing a particular ache or discovering a particular area means one thing completely different. Techie founders can construct one thing that’s utilized by their associates, however there’s no income.
  • 5:03: This occurs in every single place, however there’s an even bigger tradition round that right here. I inform founders, “It is advisable to present me traction.” We’ve got a number of firms that began as open supply, then they constructed a paid layer on high of the open supply challenge.
  • 5:34: You’re employed with the parents at Azure, so presumably you recognize what precise enterprises are doing with generative AI. Are you able to give us an thought of what enterprises are beginning to deploy? What’s the degree of consolation of enterprise with these applied sciences?
  • 6:06: Enterprises are a bit bit behind startups. Startups are constructing brokers. Enterprises should not there but. There’s lots of heavy lifting on the information infrastructure that they should have in place. And their use circumstances are complicated. It’s just like Huge Knowledge, the place the enterprise took longer to optimize their stack.
  • 7:19: Are you able to describe why enterprises must modernize their knowledge stack? 
  • 7:42: Actuality isn’t magic. There’s lots of complexity in knowledge and the way knowledge is dealt with. There may be lots of knowledge safety and privateness that startups aren’t conscious of however are necessary to enterprises. Even the varieties of knowledge—the information isn’t effectively organized, there are completely different groups utilizing completely different knowledge sources.
  • 8:28: Is RAG now a well-established sample within the enterprise?
  • 8:44: It’s. RAG is a part of all people’s workflow.
  • 8:51: The widespread use circumstances that appear to be additional alongside are buyer assist, coding—what different buckets are you able to add?
  • 9:07: Buyer assist and tickets are among the many predominant pains and use circumstances. And they’re very costly. So it’s a straightforward win for enterprises after they transfer to GenAI or AI brokers. 
  • 9:48: Are you saying that the instrument builders are forward of the instrument patrons?
  • 10:05: You’re proper. I speak so much with startups constructing brokers. We talk about the place the business is heading and what the challenges are. For those who suppose we’re near AGI, attempt to construct an agent and also you’ll see how far we’re from AGI. If you need to scale, there’s one other degree of problem. After I ask for actual examples and prospects, the bulk should not there but.
  • 11:01: A part of it’s the terminology. Folks use the time period “agent” even for a chatbot. There’s lots of confusion. And startups are hyping the notion of multiagents. We are going to get there, however let’s begin with single brokers first. And you continue to want a human within the loop. 
  • 11:40: Sure, we speak concerning the human within the loop on a regular basis. Even people who find themselves bragging, while you ask them to indicate you, they’re not there but.
  • 12:00: On the agent entrance, if I requested you for a brief presentation with three slides of examples that caught your consideration, what would they be?
  • 12:30: There’s an organization doing an AI agent with emails and your calendar. Everybody makes use of e-mail and calendars all day lengthy. If we need to schedule dinner with a bunch of associates, however we’ve got folks with dietary restrictions, it will take endlessly to discover a restaurant that checks all of the packing containers. There’s an organization attempting to make this automated.
  • 14:22: In current months, builders have rallied round MCP and now A2A. Somebody requested me for an inventory of vetted MCP servers. If the server comes from the corporate that developed the appliance, high-quality. However there are literally thousands of servers, and I’m cautious. We have already got software program provide chain points. Is MCP taking off, or is it a brief repair?
  • 15:48: It’s too early to say that that is it. There’s additionally the Google protocol (A2A); IBM created a protocol; that is an ongoing dialogue, and since it’s evolving so quick, one thing will most likely come within the subsequent few months.
  • 16:31: It’s very very like the web and the requirements that emerged from there. You can also make it formal, or you possibly can simply construct it, develop it, and one way or the other it turns into an empirical open commonplace.
  • 17:15: We’re implicitly speaking about textual content. Have you ever began to see near-production use circumstances involving multimodal fashions?
  • 17:37: We’ve seen some use circumstances with multimodality, which is extra complicated.
  • 17:48: Now you must develop your knowledge technique to all these completely different knowledge sorts.
  • 18:07: Going again to the slides: If I had three slides, I’d attempt to get everybody on the identical web page about what an AI agent is. All the massive firms have their very own definitions. I’d set the stage with my definition: a system that may take motion in your half. Then I’d say, when you suppose we’re near AGI, attempt to construct an agent. And the third slide could be to construct one agent, fairly than a multiagent. Begin small, after which you possibly can scale, not the opposite method round.
  • 19:44: Orchestration of 1 agent is one factor. Lots of people throw across the time period orchestration. For knowledge engineering, orchestration means one thing particular, and so much goes into it, even for a single agent. For multiagents, it’s much more complicated. There’s orchestration and there’s communication too. An agent could withhold, ignore, or misunderstand info. So keep on with one agent. Get that completed and transfer ahead.
  • 20:33: The large factor within the foundational mannequin house is reasoning. What has reasoning opened up for a few of these startups? What functions depend on a reasoning-enhanced mannequin? What mannequin ought to I exploit, and may I get by with a mannequin that doesn’t motive?
  • 21:15: I haven’t seen any startup utilizing reasoning but. Most likely due to what you’re speaking about. It’s costly, it’s slower, and startups must see wins quick. 
  • 21:46: They simply ask for extra free credit.
  • 21:51: Free credit should not endlessly. Nevertheless it’s not even the fee—it’s additionally the method and the ready. What are the trade-offs? I haven’t seen startups speaking with me about utilizing reasoning.
  • 22:22: The sound recommendation for anybody constructing something is to be mannequin agnostic. Design what you’re doing so you should use a number of fashions or change fashions. We now have open weights fashions which are changing into extra aggressive. Final 12 months we had Llama; now we even have Qwen and DeepSeek, with an unimaginable launch cadence. Are you seeing extra startups choosing open weights?
  • 23:19: Positively. However they should be very cautious after they use open fashions due to safety. I see lots of firms utilizing DeepSeek. I ask them about safety.
  • 23:43: Within the open weights world, you possibly can have spinoff fashions. Who vets the derivatives? Proprietary fashions have much more management. And there’s provide chain dangers, although they’re not distinctive to the open weights fashions. All of us rely on Python and Python libraries.
  • 25:17: And with folks forking spinoff fashions. . . We’ve seen this with merchandise as effectively; folks constructing merchandise and being worthwhile on high of open supply initiatives. Folks constructed on a fork of a Python challenge or high of Python libraries and [became] worthwhile. 
  • 25:55: With the Chinese language open weights fashions, I’ve talked to safety folks, and there’s nothing inherently insecure about utilizing the weights. There is likely to be architectural variations. However when you’re utilizing one of many Chinese language fashions of their open API, they may have to show over knowledge. Usually, entry to the weights isn’t a typical assault vector.
  • 27:03: Or you should use firms like Microsoft. We’ve got DeepSeek R1 obtainable on Azure. Nevertheless it’s gone by way of rigorous red-teaming and security analysis to mitigate dangers. 
  • 27:39: There are variations when it comes to alignment and red-teaming between Western and Chinese language firms.
  • 28:26: In closing, are there any parallels between what you’re seeing now and what we noticed in knowledge science?
  • 28:40: It’s related, however the scale and velocity are completely different. There are extra assets and accessibility. The barrier to entry is decrease. 
  • 29:06: The hype cycle is similar. You bear in mind all of the tales about “Knowledge science is the attractive new job.” However the know-how is now rather more accessible, and there are much more tales and extra pleasure.
  • 29:29: Again then, we solely had just a few choices: Hadoop, Spark. . . Not like 100 completely different fashions. And so they weren’t accessible to most people. 
  • 30:03: Again then folks didn’t want Hadoop or MapReduce or Spark in the event that they didn’t have a lot of knowledge. And now, you don’t have to make use of the brightest or best-benchmarked LLM; you should use a small language mannequin.

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